Since there are no systematic studies available on the effects of anti-microtubule agents on
ciliated protozoa, we screened a wide variety of such compounds for their effects on the
growth of Paramecium tetraurelia cell cultures. Compounds tested include agents of widely
different chemical composition and with reported effects on widely different cell types. We
can differentiate between different drug effects:(a) Rotenone is the only agent without any
recognisable effect,(b) Another group of compounds (including colchicine) requires very …